Dual Roles for the TSPYL Family in Mediating Serotonin Transport and the Metabolism of Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder

We previously reported that testis‐specific Y‐encoded‐like protein (TSPYLs) are transcription regulators for CYP3A4, CYP2C9, and CYP2C19. Here, we observed dual roles for TSPYLs in mediating serotonin transport and the metabolism of selective serotonin reuptake inhibitors (SSRIs) in patients with ma...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Ther
Main Authors: Qin, Sisi, Eugene, Andy R., Liu, Duan, Zhang, Lingxin, Neavin, Drew, Biernacka, Joanna M., Yu, Jia, Weinshilboum, Richard M., Wang, Liewei
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018538/
https://ncbi.nlm.nih.gov/pubmed/31628858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1692
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