FKBP5 genetic variation: association with selective serotonin reuptake inhibitor treatment outcomes in major depressive disorder

OBJECTIVES: FKBP51 (51 kDa immunophilin) acts as a modulator of the glucocorticoid receptor and a negative regulator of the Akt pathway. Genetic variation in FKBP5 plays a role in antidepressant response. The aim of this study was to comprehensively assess the role of genetic variation in FKBP5, ide...

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Detalhes bibliográficos
Main Authors: Ellsworth, Katarzyna A., Moon, Irene, Eckloff, Bruce W., Fridley, Brooke L., Jenkins, Gregory D., Batzler, Anthony, Biernacka, Joanna M., Abo, Ryan, Brisbin, Abra, Ji, Yuan, Hebbring, Scott, Wieben, Eric D., Mrazek, David A., Weinshilboum, Richard M., Wang, Liewei
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784025/
https://ncbi.nlm.nih.gov/pubmed/23324805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e32835dc133
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