Intranasal Nanoemulsion-Adjuvanted HSV-2 Subunit Vaccine is Effective as a Prophylactic and Therapeutic Vaccine Using the Guinea Pig Model of Genital Herpes

Genital herpes is a sexually transmitted disease representing a major global health concern. Currently, there is no approved vaccine and existing antiviral therapies exhibit limited efficacy. Herein, we describe an intranasal (IN) vaccine comprised of HSV-2 surface glycoproteins gD2 and gB2 formulat...

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Bibliografiske detaljer
Udgivet i:Vaccine
Main Authors: Bernstein, David, Cardin, Rhonda, Bravo, Fernando, Hamouda, Tarek, Pullum, Derek, Cohen, Gary, Bitko, Vira, Fattom, Ali
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017967/
https://ncbi.nlm.nih.gov/pubmed/31515143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2019.08.077
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