Intranasal Nanoemulsion-Adjuvanted HSV-2 Subunit Vaccine is Effective as a Prophylactic and Therapeutic Vaccine Using the Guinea Pig Model of Genital Herpes

Genital herpes is a sexually transmitted disease representing a major global health concern. Currently, there is no approved vaccine and existing antiviral therapies exhibit limited efficacy. Herein, we describe an intranasal (IN) vaccine comprised of HSV-2 surface glycoproteins gD2 and gB2 formulat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Vaccine
Prif Awduron: Bernstein, David, Cardin, Rhonda, Bravo, Fernando, Hamouda, Tarek, Pullum, Derek, Cohen, Gary, Bitko, Vira, Fattom, Ali
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017967/
https://ncbi.nlm.nih.gov/pubmed/31515143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2019.08.077
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg