Loading...

A nuclear phosphoinositide kinase complex regulates p53

The tumor suppressor p53 (TP53) protects the genome against cellular stress and is frequently mutated in cancer. Mutant p53 acquires gain-of-function oncogenic activities that are dependent on its enhanced stability. However, the mechanisms by which nuclear p53 is stabilized are poorly understood. H...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Cell Biol
Main Authors: Choi, Suyong, Chen, Mo, Cryns, Vincent L., Anderson, Richard A.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017954/
https://ncbi.nlm.nih.gov/pubmed/30886346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-019-0297-2
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!