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The Loss of p21-Activated Kinase (Pak1) Promotes Atrial Arrhythmic Activity: The Role of Pak1 in Atrial Arrhythmia

BACKGROUND: Atrial fibrillation (AF) is initiated through arrhythmic atrial excitation from outside the sinus node or remodeling of atrial tissue that allows reentry of excitation. Angiotensin II (AngII) has been implicated in initiation and maintenance of AF through changes in Ca(2+) handling and p...

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Bibliographische Detailangaben
Veröffentlicht in:Heart Rhythm
Hauptverfasser: DeSantiago, Jaime, Bare, Dan J., Varma, Disha, Solaro, R. John, Arora, Rishi, Banach, Kathrin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017889/
https://ncbi.nlm.nih.gov/pubmed/29625277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2018.03.041
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