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The Loss of p21-Activated Kinase (Pak1) Promotes Atrial Arrhythmic Activity: The Role of Pak1 in Atrial Arrhythmia

BACKGROUND: Atrial fibrillation (AF) is initiated through arrhythmic atrial excitation from outside the sinus node or remodeling of atrial tissue that allows reentry of excitation. Angiotensin II (AngII) has been implicated in initiation and maintenance of AF through changes in Ca(2+) handling and p...

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Detalhes bibliográficos
Publicado no:Heart Rhythm
Main Authors: DeSantiago, Jaime, Bare, Dan J., Varma, Disha, Solaro, R. John, Arora, Rishi, Banach, Kathrin
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017889/
https://ncbi.nlm.nih.gov/pubmed/29625277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2018.03.041
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