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Rationale‐based selection of optimal operating strategies and gene dosage impact on recombinant protein production in Komagataella phaffii (Pichia pastoris)

Its features as a microbial and eukaryotic organism have turned Komagataella phaffii (Pichia pastoris) into an emerging cell factory for recombinant protein production (RPP). As a key step of the bioprocess development, this work aimed to demonstrate the importance of tailor designing the cultivatio...

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Detalhes bibliográficos
Publicado no:Microb Biotechnol
Main Authors: Nieto‐Taype, Miguel Angel, Garrigós‐Martínez, Javier, Sánchez‐Farrando, Marc, Valero, Francisco, Garcia‐Ortega, Xavier, Montesinos‐Seguí, José Luis
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017824/
https://ncbi.nlm.nih.gov/pubmed/31657146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1751-7915.13498
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