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Emerging therapeutic targets for neurofibromatosis type 1 (NF1)

INTRODUCTION: Neurofibromatosis type 1 (NF1) is an autosomal dominantly inherited tumor predisposition syndrome with an incidence of one in 3000–4000 individuals with no currently effective therapies. The NF1 gene on chromosome 17 encodes neurofibromin, which functions as a negative regulator of RAS...

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Bibliografske podrobnosti
izdano v:Expert Opin Ther Targets
Main Authors: Walker, James A., Upadhyaya, Meena
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017752/
https://ncbi.nlm.nih.gov/pubmed/29667529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14728222.2018.1465931
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