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Emerging therapeutic targets for neurofibromatosis type 1 (NF1)
INTRODUCTION: Neurofibromatosis type 1 (NF1) is an autosomal dominantly inherited tumor predisposition syndrome with an incidence of one in 3000–4000 individuals with no currently effective therapies. The NF1 gene on chromosome 17 encodes neurofibromin, which functions as a negative regulator of RAS...
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| Опубликовано в: : | Expert Opin Ther Targets |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7017752/ https://ncbi.nlm.nih.gov/pubmed/29667529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14728222.2018.1465931 |
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