The aberrant expression of ADAR1 promotes resistance to BET inhibitors in pancreatic cancer by stabilizing c-Myc

Pancreatic cancer is a malignant tumor with the worst prognosis worldwide. This cancer type requires new insight to help with diagnosis and, eventually, treatment. Adenosine deaminases acting on RNA 1 (ADAR1) is reportedly overexpressed in many types of tumors, such as lung, liver, breast, and esoph...

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Опубликовано в: :Am J Cancer Res
Главные авторы: Sun, Yan, Fan, Jiquan, Wang, Bo, Meng, Zibo, Ren, Dianyun, Zhao, Jingyuan, Liu, Zhiqiang, Li, Dan, Jin, Xin, Wu, Heshui
Формат: Artigo
Язык:Inglês
Опубликовано: e-Century Publishing Corporation 2020
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017738/
https://ncbi.nlm.nih.gov/pubmed/32064158
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