Safety and pharmacodynamics of anti-CD2 monoclonal antibody treatment in cynomolgus macaques

BACKGROUND: Anti-CD2 treatment provides targeted immunomodulatory properties that have demonstrated clinical usefulness to condition the immune system and to treat transplant rejection. The treatment is species-specific due to structural CD2 antigen differences between non-human primates and humans....

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Publicat a:Transpl Int
Autors principals: Berglund, Erik, Alonso-Guallart, Paula, Danton, Makenzie, Sellberg, Felix, Binder, Christian, Fröbom, Robin, Berglund, David, Llore, Nathaly, Sakai, Hiroshi, Iuga, Alina, Ekanayake-Alper, Dilrukshi, Reimann, Keith A., Sachs, David H, Sykes, Megan, Griesemer, Adam
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017722/
https://ncbi.nlm.nih.gov/pubmed/31523849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tri.13524
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