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Alcohol-Mediated Calcium Signals Dysregulate Pro-Survival Snai2/PUMA/Bcl2 Networks to Promote p53-Mediated Apoptosis in Avian Neural Crest Progenitors
BACKGROUND: Prenatal alcohol exposure (PAE) causes distinctive craniofacial anomalies that arise, in part, from the apoptotic elimination of neural crest (NC) progenitors that form the face. This vulnerability of NC to alcohol is puzzling as they normally express the transcriptional repressor Snail1...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Birth Defects Res |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7017393/ https://ncbi.nlm.nih.gov/pubmed/31021056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdr2.1508 |
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