Modulating Tumor-Associated Macrophage Polarization by Synthetic and Natural PPARγ Ligands as a Potential Target in Breast Cancer

Activation of peroxisome proliferator-activated receptor gamma (PPARγ) elicits anti-proliferative effects on different tumor cells, including those derived from breast cancer. PPARγ is also expressed in several cells of the breast tumor microenvironment, among which tumor associated macrophages (TAM...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Gionfriddo, Giulia, Plastina, Pierluigi, Augimeri, Giuseppina, Catalano, Stefania, Giordano, Cinzia, Barone, Ines, Morelli, Catia, Giordano, Francesca, Gelsomino, Luca, Sisci, Diego, Witkamp, Renger, Andò, Sebastiano, van Norren, Klaske, Bonofiglio, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017381/
https://ncbi.nlm.nih.gov/pubmed/31936729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010174
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