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Cytokine Directed Chondroblast Trans-Differentiation: JAK Inhibition Facilitates Direct Reprogramming of Fibroblasts to Chondroblasts

Osteoarthritis (OA) is a degenerative disease of the hyaline articular cartilage. This disease is progressive and may lead to disability. Researchers proposed many regenerative approaches to treat osteoarthritis, including stem cells. Trans-differentiation of a fully differentiated cell state direct...

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Vydáno v:Cells
Hlavní autoři: Cota, Perla, Helmi, Summer A., Hsu, Charlie, Rancourt, Derrick E.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017373/
https://ncbi.nlm.nih.gov/pubmed/31940860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010191
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