SSEA3 and Sialyl Lewis a Glycan Expression Is Controlled by B3GALT5 LTR through Lamin A-NFYA and SIRT1-STAT3 Signaling in Human ES Cells

B3GALT5 is involved in the synthesis of embryonic stem (ES) cell marker glycan, stage-specific embryonic antigen-3 (SSEA3). This gene has three native promoters and an integrated retroviral long terminal repeat (LTR) promoter. We found that B3GALT5-LTR is expressed at high levels in human ES cells....

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Pubblicato in:Cells
Autori principali: Cai, Bi-He, Lee, Hsueh-Yi, Chou, Chi-Kan, Wu, Po-Han, Huang, Hsiang-Chi, Chao, Chia-Chun, Chung, Hsiao-Yu, Kannagi, Reiji
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017369/
https://ncbi.nlm.nih.gov/pubmed/31936807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010177
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