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Stromal Features of the Primary Tumor Are Not Prognostic in Genetically Engineered Mice of Pancreatic Cancer

The Kras(G12D/+);LSL-Trp53(R172H/+);Pdx-1-Cre (KPC) mouse model is frequently employed for preclinical therapeutic testing, in particular in regard to antistromal therapies. Here, we investigate the prognostic implications of histopathological features that may guide preclinical trial design. Pancre...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Hasselluhn, Marie C., Klein, Lukas, Patzak, Melanie S., Buchholz, Sören M., Ströbel, Philipp, Ellenrieder, Volker, Maisonneuve, Patrick, Neesse, Albrecht
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017324/
https://ncbi.nlm.nih.gov/pubmed/31878349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010058
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