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The Diverse Roles of TIMP-3: Insights into Degenerative Diseases of the Senescent Retina and Brain

Tissue inhibitor of metalloproteinase-3 (TIMP-3) is a component of the extracellular environment, where it mediates diverse processes including matrix regulation/turnover, inflammation and angiogenesis. Rare TIMP-3 risk alleles and mutations are directly linked with retinopathies such as age-related...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Dewing, Jennifer M., Carare, Roxana O., Lotery, Andrew J., Ratnayaka, J. Arjuna
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017234/
https://ncbi.nlm.nih.gov/pubmed/31877820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010039
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