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Mfn2 Ablation in the Adult Mouse Hippocampus and Cortex Causes Neuronal Death

It is believed that mitochondrial fragmentation cause mitochondrial dysfunction and neuronal deficits in Alzheimer’s disease. We recently reported that constitutive knockout of the mitochondria fusion protein mitofusin2 (Mfn2) in the mouse brain causes mitochondrial fragmentation and neurodegenerati...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Han, Song, Nandy, Priya, Austria, Quillan, Siedlak, Sandra L., Torres, Sandy, Fujioka, Hisashi, Wang, Wenzhang, Zhu, Xiongwei
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017224/
https://ncbi.nlm.nih.gov/pubmed/31947766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010116
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