Cirrhotic Human Liver Extracellular Matrix 3D Scaffolds Promote Smad-Dependent TGF-β1 Epithelial Mesenchymal Transition

An altered liver microenvironment characterized by a dysregulated extracellular matrix (ECM) supports the development and progression of hepatocellular carcinoma (HCC). The development of experimental platforms able to reproduce these physio-pathological conditions is essential in order to identify...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Mazza, Giuseppe, Telese, Andrea, Al-Akkad, Walid, Frenguelli, Luca, Levi, Ana, Marrali, Martina, Longato, Lisa, Thanapirom, Kessarin, Vilia, Maria Giovanna, Lombardi, Benedetta, Crowley, Claire, Crawford, Mark, Karsdal, Morten A., Leeming, Diana J., Marrone, Giusi, Bottcher, Katrin, Robinson, Benjamin, Del Rio Hernandez, Armando, Tamburrino, Domenico, Spoletini, Gabriele, Malago, Massimo, Hall, Andrew R., Godovac-Zimmermann, Jasminka, Luong, Tu Vinh, De Coppi, Paolo, Pinzani, Massimo, Rombouts, Krista
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017194/
https://ncbi.nlm.nih.gov/pubmed/31905709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010083
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