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Clustered DNA Double-Strand Breaks: Biological Effects and Relevance to Cancer Radiotherapy

Cells manage to survive, thrive, and divide with high accuracy despite the constant threat of DNA damage. Cells have evolved with several systems that efficiently repair spontaneous, isolated DNA lesions with a high degree of accuracy. Ionizing radiation and a few radiomimetic chemicals can produce...

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Bibliographic Details
Published in:Genes (Basel)
Main Authors: Nickoloff, Jac A., Sharma, Neelam, Taylor, Lynn
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017136/
https://ncbi.nlm.nih.gov/pubmed/31952359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11010099
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