Mutant IDH1 Depletion Downregulates Integrins and Impairs Chondrosarcoma Growth

Chondrosarcomas are a heterogeneous group of malignant bone tumors that produce hyaline cartilaginous matrix. Mutations in isocitrate dehydrogenase enzymes (IDH1/2) were recently described in several cancers, including conventional and dedifferentiated chondrosarcomas. These mutations lead to the in...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Li, Luyuan, Hu, Xiaoyu, Eid, Josiane E., Rosenberg, Andrew E., Wilky, Breelyn A., Ban, Yuguang, Sun, Xiaodian, Galoian, Karina, DeSalvo, Joanna, Yue, Jinbo, Chen, Xi Steven, Blonska, Marzenna, Trent, Jonathan C.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017040/
https://ncbi.nlm.nih.gov/pubmed/31935911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12010141
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