Binding and Regulation of Transcription by Yeast Ste12 Variants To Drive Mating and Invasion Phenotypes

Amino acid substitutions are commonly found in human transcription factors, yet the functional consequences of much of this variation remain unknown, even in well-characterized DNA-binding domains. Here, we examine how six single-amino acid variants in the DNA-binding domain of Ste12—a yeast transcr...

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Bibliographic Details
Published in:Genetics
Main Authors: Zhou, Wei, Dorrity, Michael W., Bubb, Kerry L., Queitsch, Christine, Fields, Stanley
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2020
Subjects:
Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017024/
https://ncbi.nlm.nih.gov/pubmed/31810988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302929
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