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Pharmacological Inhibition of Oncogenic STAT3 and STAT5 Signaling in Hematopoietic Cancers

Signal Transducer and Activator of Transcription (STAT) 3 and 5 are important effectors of cellular transformation, and aberrant STAT3 and STAT5 signaling have been demonstrated in hematopoietic cancers. STAT3 and STAT5 are common targets for different tyrosine kinase oncogenes (TKOs). In addition,...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Brachet-Botineau, Marie, Polomski, Marion, Neubauer, Heidi A., Juen, Ludovic, Hédou, Damien, Viaud-Massuard, Marie-Claude, Prié, Gildas, Gouilleux, Fabrice
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016966/
https://ncbi.nlm.nih.gov/pubmed/31963765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12010240
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