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Effect of Cysteine on Methylglyoxal-Induced Renal Damage in Mesangial Cells

Methylglyoxal (MGO), a highly reactive dicarbonyl compound, is a key precursor of the formation of advanced glycation end products (AGEs). MGO and MGO-AGEs were reportedly increased in patients with diabetic dysfunction, including diabetic nephropathy. The activation of glyoxalase-I (GLO-I) increase...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Lee, Jae Hyuk, Subedi, Lalita, Kim, Sun Yeou
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016887/
https://ncbi.nlm.nih.gov/pubmed/31963523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010234
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