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Differential Depletion of Bone Marrow Resident B-ALL after Systemic Administration of Endosomal TLR Agonists

Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy. While frontline chemotherapy regimens are generally very effective, the prognosis for patients whose leukemia returns remains poor. The presence of measurable residual disease (MRD) in bone marrow at the completion of induct...

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Publicat a:Cancers (Basel)
Autors principals: Jo, Sumin, Fotovati, Abbas, Duque-Afonso, Jesus, Cleary, Michael L., van den Elzen, Peter, Seif, Alix E., Reid, Gregor S.D.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016792/
https://ncbi.nlm.nih.gov/pubmed/32015298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12010169
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