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Candidate Causal Variants at the 8p12 Breast Cancer Risk Locus Regulate DUSP4

Genome-wide association studies have revealed a locus at 8p12 that is associated with breast cancer risk. Fine-mapping of this locus identified 16 candidate causal variants (CCVs). However, as these variants are intergenic, their function is unclear. To map chromatin looping from this risk locus to...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cancers (Basel)
मुख्य लेखकों: Glubb, Dylan M., Shi, Wei, Beesley, Jonathan, Fachal, Laura, Pritchard, Jayne-Louise, McCue, Karen, Barnes, Daniel R., Antoniou, Antonis C., Dunning, Alison M., Easton, Douglas F., Chenevix-Trench, Georgia
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016765/
https://ncbi.nlm.nih.gov/pubmed/31936698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12010170
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