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Transcriptional Suppression of the NLRP3 Inflammasome and Cytokine Release in Primary Macrophages by Low-Dose Anthracyclines

Tissue-resident macrophages play critical roles in controlling homeostasis, tissue repair, and immunity. Inflammatory macrophages can sustain tissue damage and promote the development of fibrosis during infections and sterile tissue injury. The NLRP3 inflammasome and its effector cytokine IL-1β have...

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Publicado en:Cells
Main Authors: Köse-Vogel, Nilay, Stengel, Sven, Gardey, Elena, Kirchberger-Tolstik, Tatiana, Reuken, Philipp A., Stallmach, Andreas, Bruns, Tony
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016608/
https://ncbi.nlm.nih.gov/pubmed/31905600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010079
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