Compliant Substrates Enhance Macrophage Cytokine Release and NLRP3 Inflammasome Formation During Their Pro-Inflammatory Response

Immune cells process a myriad of biochemical signals but their function and behavior are also determined by mechanical cues. Macrophages are no exception to this. Being present in all types of tissues, macrophages are exposed to environments of varying stiffness, which can be further altered under p...

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Udgivet i:Front Cell Dev Biol
Main Authors: Escolano, Joan-Carles, Taubenberger, Anna V., Abuhattum, Shada, Schweitzer, Christine, Farrukh, Aleeza, del Campo, Aránzazu, Bryant, Clare E., Guck, Jochen
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Cell and Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8039395/
https://ncbi.nlm.nih.gov/pubmed/33855019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.639815
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