A Novel Prostate Cell Type-Specific Gene Signature to Interrogate Prostate Tumor Differentiation Status and Monitor Therapeutic Response (Running Title: Phenotypic Classification of Prostate Tumors)

In this study, we extracted prostate cell-specific gene sets (metagenes) to define the epithelial differentiation status of prostate cancers and, using a deconvolution-based strategy, interrogated thousands of primary and metastatic tumors in public gene profiling datasets. We identified a subgroup...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Mapelli, Sarah N., Albino, Domenico, Mello-Grand, Maurizia, Shinde, Dheeraj, Scimeca, Manuel, Bonfiglio, Rita, Bonanno, Elena, Chiorino, Giovanna, Garcia-Escudero, Ramon, Catapano, Carlo V., Carbone, Giuseppina M.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016595/
https://ncbi.nlm.nih.gov/pubmed/31936761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12010176
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