TDP-43-Mediated Toxicity in HEK293T Cells: A Fast and Reproducible Protocol To Be Employed in the Search of New Therapeutic Options against Amyotrophic Lateral Sclerosis

Cytoplasmic TDP-43 aggregates are a hallmark of amyotrophic lateral sclerosis (ALS). Today, only two drugs are available for ALS treatment, and their modest effect prompts researchers to search for new therapeutic options. TDP-43 represents one of the most promising targets for therapeutic intervent...

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Publicado en:Cells
Main Authors: Lanznaster, Débora, Bourgeais, Jérôme, Bruno, Clement, Hergesheimer, Rudolf C., Thepault, Rose-Anne, Vourc’h, Patrick, Corcia, Philippe, Andres, Christian R., Herault, Olivier, Blasco, Hélène
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016571/
https://ncbi.nlm.nih.gov/pubmed/31888078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010068
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