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The debated toxic role of aggregated TDP-43 in amyotrophic lateral sclerosis: a resolution in sight?
Transactive response DNA-binding protein-43 (TDP-43) is an RNA/DNA binding protein that forms phosphorylated and ubiquitinated aggregates in the cytoplasm of motor neurons in amyotrophic lateral sclerosis, which is a hallmark of this disease. Amyotrophic lateral sclerosis is a neurodegenerative cond...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Brain |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Oxford University Press
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6487324/ https://ncbi.nlm.nih.gov/pubmed/30938443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awz078 |
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