Plasmodium Condensin Core Subunits SMC2/SMC4 Mediate Atypical Mitosis and Are Essential for Parasite Proliferation and Transmission

Condensin is a multi-subunit protein complex regulating chromosome condensation and segregation during cell division. In Plasmodium spp., the causative agent of malaria, cell division is atypical and the role of condensin is unclear. Here we examine the role of SMC2 and SMC4, the core subunits of co...

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Pubblicato in:Cell Rep
Autori principali: Pandey, Rajan, Abel, Steven, Boucher, Matthew, Wall, Richard J., Zeeshan, Mohammad, Rea, Edward, Freville, Aline, Lu, Xueqing Maggie, Brady, Declan, Daniel, Emilie, Stanway, Rebecca R., Wheatley, Sally, Batugedara, Gayani, Hollin, Thomas, Bottrill, Andrew R., Gupta, Dinesh, Holder, Anthony A., Le Roch, Karine G., Tewari, Rita
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016506/
https://ncbi.nlm.nih.gov/pubmed/32049018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.01.033
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