Plasmodium Condensin Core Subunits SMC2/SMC4 Mediate Atypical Mitosis and Are Essential for Parasite Proliferation and Transmission

Condensin is a multi-subunit protein complex regulating chromosome condensation and segregation during cell division. In Plasmodium spp., the causative agent of malaria, cell division is atypical and the role of condensin is unclear. Here we examine the role of SMC2 and SMC4, the core subunits of co...

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Gepubliceerd in:Cell Rep
Hoofdauteurs: Pandey, Rajan, Abel, Steven, Boucher, Matthew, Wall, Richard J., Zeeshan, Mohammad, Rea, Edward, Freville, Aline, Lu, Xueqing Maggie, Brady, Declan, Daniel, Emilie, Stanway, Rebecca R., Wheatley, Sally, Batugedara, Gayani, Hollin, Thomas, Bottrill, Andrew R., Gupta, Dinesh, Holder, Anthony A., Le Roch, Karine G., Tewari, Rita
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016506/
https://ncbi.nlm.nih.gov/pubmed/32049018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.01.033
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