Transcription factor NRF2 uses the Hippo pathway effector TAZ to induce tumorigenesis in glioblastomas

Transcription factor NRF2 orchestrates a cellular defense against oxidative stress and, so far, has been involved in tumor progression by providing a metabolic adaptation to tumorigenic demands and resistance to chemotherapeutics. In this study, we discover that NRF2 also propels tumorigenesis in gl...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Redox Biol
Prif Awduron: Escoll, Maribel, Lastra, Diego, Pajares, Marta, Robledinos-Antón, Natalia, Rojo, Ana I., Fernández-Ginés, Raquel, Mendiola, Marta, Martínez-Marín, Virginia, Esteban, Isabel, López-Larrubia, Pilar, Gargini, Ricardo, Cuadrado, Antonio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2020
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016245/
https://ncbi.nlm.nih.gov/pubmed/31918259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101425
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