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Nuclear Factor-Kappa Beta Signaling is Required for Transforming Growth Factor Beta-2 Induced Ocular Hypertension

A major risk for the development of primary open-angle glaucoma (POAG) is elevated intraocular pressure (IOP). Elevated IOP is caused by increased outflow resistance due in part to excessive extracellular matrix (ECM) deposition in the trabecular meshwork (TM). The role of transforming growth factor...

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Publicat a:Exp Eye Res
Autors principals: Hernandez, Humberto, Roberts, Amanda L., McDowell, Colleen M.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7015797/
https://ncbi.nlm.nih.gov/pubmed/31923415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2020.107920
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