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Specificity and mutagenesis bias of the mycobacterial alternative mismatch repair analyzed by mutation accumulation studies

The postreplicative mismatch repair (MMR) is an almost ubiquitous DNA repair essential for maintaining genome stability. It has been suggested that Mycobacteria have an alternative MMR in which NucS, an endonuclease with no structural homology to the canonical MMR proteins (MutS/MutL), is the key fa...

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Publicado en:Sci Adv
Autores principales: Castañeda-García, A., Martín-Blecua, I., Cebrián-Sastre, E., Chiner-Oms, A., Torres-Puente, M., Comas, I., Blázquez, J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Association for the Advancement of Science 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7015689/
https://ncbi.nlm.nih.gov/pubmed/32095527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay4453
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