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Simple Sequence Repeats and Mucoid Conversion: Biased mucA Mutagenesis in Mismatch Repair-Deficient Pseudomonas aeruginosa

In Pseudomonas aeruginosa, conversion to the mucoid phenotype marks the onset of an irreversible state of the infection in Cystic Fibrosis (CF) patients. The main pathway for mucoid conversion is mutagenesis of the mucA gene, frequently due to −1 bp deletions in a simple sequence repeat (SSR) of 5 G...

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Bibliografische gegevens
Hoofdauteurs: Moyano, Alejandro J., Smania, Andrea M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781719/
https://ncbi.nlm.nih.gov/pubmed/19997602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008203
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