Broadly conserved roles of TMEM131 family proteins in intracellular collagen assembly and secretory cargo trafficking

Collagen is the most abundant protein in animals. Its dysregulation contributes to aging and many human disorders, including pathological tissue fibrosis in major organs. How premature collagen proteins in the endoplasmic reticulum (ER) assemble and route for secretion remains molecularly undefined....

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Zhang, Zhe, Bai, Meirong, Barbosa, Guilherme Oliveira, Chen, Andrew, Wei, Yuehua, Luo, Shuo, Wang, Xin, Wang, Bingying, Tsukui, Tatsuya, Li, Hao, Sheppard, Dean, Kornberg, Thomas B., Ma, Dengke K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7015688/
https://ncbi.nlm.nih.gov/pubmed/32095531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay7667
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