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The conserved autoimmune-disease risk gene TMEM39A regulates lysosome dynamics
TMEM39A encodes an evolutionarily conserved transmembrane protein and carries single-nucleotide polymorphisms associated with increased risk of major human autoimmune diseases, including multiple sclerosis. The exact cellular function of TMEM39A remains not well understood. Here, we report that TMEM...
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| izdano v: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2021
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8017986/ https://ncbi.nlm.nih.gov/pubmed/33531362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2011379118 |
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