The conserved autoimmune-disease risk gene TMEM39A regulates lysosome dynamics

TMEM39A encodes an evolutionarily conserved transmembrane protein and carries single-nucleotide polymorphisms associated with increased risk of major human autoimmune diseases, including multiple sclerosis. The exact cellular function of TMEM39A remains not well understood. Here, we report that TMEM...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Luo, Shuo, Wang, Xin, Bai, Meirong, Jiang, Wei, Zhang, Zhe, Chen, Yifan, Ma, Dengke K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2021
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8017986/
https://ncbi.nlm.nih.gov/pubmed/33531362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2011379118
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