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Marked structural rearrangement of mannose 6-phosphate/IGF2 receptor at different pH environments
Many cell surface receptors internalize their ligands and deliver them to endosomes, where the acidic pH causes the ligand to dissociate. The liberated receptor returns to the cell surface in a process called receptor cycling. The structural basis for pH-dependent ligand dissociation is not well und...
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| Publicado en: | Sci Adv |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Association for the Advancement of Science
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7015683/ https://ncbi.nlm.nih.gov/pubmed/32095534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz1466 |
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