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Cryo-EM structures of undocked innexin-6 hemichannels in phospholipids

Gap junctions form intercellular conduits with a large pore size whose closed and open states regulate communication between adjacent cells. The structural basis of the mechanism by which gap junctions close, however, remains uncertain. Here, we show the cryo–electron microscopy structures of Caenor...

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Détails bibliographiques
Publié dans:Sci Adv
Auteurs principaux: Burendei, Batuujin, Shinozaki, Ruriko, Watanabe, Masakatsu, Terada, Tohru, Tani, Kazutoshi, Fujiyoshi, Yoshinori, Oshima, Atsunori
Format: Artigo
Langue:Inglês
Publié: American Association for the Advancement of Science 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7015682/
https://ncbi.nlm.nih.gov/pubmed/32095518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax3157
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