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Phylogenetic analysis reveals an ancient gene duplication as the origin of the MdtABC efflux pump

The efflux pumps from the Resistance-Nodulation-Division family, RND, are main contributors to intrinsic antibiotic resistance in Gram-negative bacteria. Among this family, the MdtABC pump is unusual by having two inner membrane components. The two components, MdtB and MdtC are homologs, therefore i...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Górecki, Kamil, McEvoy, Megan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7015380/
https://ncbi.nlm.nih.gov/pubmed/32050009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228877
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