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Phylogenetic analysis of ferlin genes reveals ancient eukaryotic origins

BACKGROUND: The ferlin gene family possesses a rare and identifying feature consisting of multiple tandem C2 domains and a C-terminal transmembrane domain. Much currently remains unknown about the fundamental function of this gene family, however, mutations in its two most well-characterised members...

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Main Authors: Lek, Angela, Lek, Monkol, North, Kathryn N, Cooper, Sandra T
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923515/
https://ncbi.nlm.nih.gov/pubmed/20667140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-10-231
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