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TNFα-mediated activation of NF-κB downregulates sodium-iodide symporter expression in thyroid cells
The sodium-iodide symporter (NIS) mediates transport of iodide across the basolateral membrane of thyroid cells. NIS expression in thyroid cancer (TC) cells allows the use of radioactive iodine (RAI) as a diagnostic and therapeutic tool, being RAI therapy the systemic treatment of choice for metasta...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7015378/ https://ncbi.nlm.nih.gov/pubmed/32049985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228794 |
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