Choroid plexus LAT2 and SNAT3 as partners in CSF amino acid homeostasis maintenance

BACKGROUND: Cerebrospinal fluid (CSF) is mainly produced by the choroid plexus (CP) located in brain ventricles. Although derived from blood plasma, it is nearly protein-free (~ 250-fold less) and contains about 2–20-fold less free amino acids, with the exception of glutamine (Gln) which is nearly e...

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Vydáno v:Fluids Barriers CNS
Hlavní autoři: Dolgodilina, Elena, Camargo, Simone M., Roth, Eva, Herzog, Brigitte, Nunes, Virginia, Palacín, Manuel, Verrey, Francois
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7014681/
https://ncbi.nlm.nih.gov/pubmed/32046769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-020-0178-x
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