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Choroid plexus genes for CSF production and brain homeostasis are altered in Alzheimer’s disease

BACKGROUND: The roles of the choroid plexus (CP) and cerebrospinal fluid (CSF) production have drawn increasing attention in Alzheimer’s disease (AD) research. Specifically, studies document markedly decreased CSF production and turnover in moderate-to-severe AD. Moreover, reduced CP function and CS...

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Detalhes bibliográficos
Publicado no:Fluids Barriers CNS
Main Authors: Kant, Shawn, Stopa, Edward G., Johanson, Conrad E., Baird, Andrew, Silverberg, Gerald D.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6291926/
https://ncbi.nlm.nih.gov/pubmed/30541599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-018-0120-7
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