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miR-124 and miR-203 synergistically inactivate EMT pathway via coregulation of ZEB2 in clear cell renal cell carcinoma (ccRCC)

BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is one of the most aggressive urological malignancies. MicroRNAs (miRNAs) are post-transcriptional gene regulators in tumor pathophysiology. As miRNAs exert cooperative repressive effects on target genes, studying the miRNA synergism is important t...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Chen, Jiajia, Zhong, Yuqing, Li, Liangzhi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7014595/
https://ncbi.nlm.nih.gov/pubmed/32046742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02242-x
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