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Over-expression of miR-34a induces rapid cognitive impairment and Alzheimer’s disease-like pathology
Autosomal dominant Alzheimer disease (AD) is caused by rare mutations in one of three specific genes. This is in contrast to idiopathic, late-onset AD (LOAD), which has a more polygenetic risk profile and represents more than 95% of cases. Previously, we have demonstrated that increased expression o...
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| 出版年: | Brain Res |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7014559/ https://ncbi.nlm.nih.gov/pubmed/31295467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2019.146327 |
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