Potentiation of Low-Dose Doxorubicin Cytotoxicity by Affecting P-Glycoprotein through Caryophyllane Sesquiterpenes in HepG2 Cells: An In Vitro and In Silico Study

Doxorubicin represents a valuable choice for different cancers, although the severe side effects occurring at the high effective dose limits its clinical use. In the present study, potential strategies to potentiate low-dose doxorubicin efficacy, including a metronomic schedule, characterized by a s...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Di Sotto, Antonella, Irannejad, Hamid, Eufemi, Margherita, Mancinelli, Romina, Abete, Lorena, Mammola, Caterina Loredana, Altieri, Fabio, Mazzanti, Gabriela, Di Giacomo, Silvia
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7014471/
https://ncbi.nlm.nih.gov/pubmed/31963614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21020633
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi